The agency on monitoring over food and medicines of the USA (FDA) approved a preparation of Revacio in the form of solution for intravenous injections for treatment of pulmonary hypertensia. Revacio is single approved FDA selective inhibitor 5 types, available both in tablets, and in solution for injections. Revacio preparation is applied at adult patients to treatment of pulmonary arterial hypertension (the I FC on WHO classification) for improving of physical possibilities of the patient and deceleration of clinical deterioration.
Deceleration of clinical deterioration was fixed in case of simultaneous therapy. Revacio efficiency in case of joint application with yet didn't receive an adequate assessment. The most widespread ghost effects treat: nasal bleeding, a headache, inflow, problems with a dream and irritation of a stomach. To Revacio in the form of injections it is intended for patients with pulmonary hypertension which for any reasons can't accept Revacio in tablets. The primary pulmonary hypertensia is caused by step-by-step narrowing of a clearance of averages and small-sized branches of a pulmonary artery with development of right ventricular insufficiency (average pressure in a pulmonary artery is higher than 25 mm Hg in rest and 30 ??.??.?? in case of physical activity). Clinical signs and symptoms of primary pulmonary hypertensia include inspiratory short wind, a thorax pains, dizziness, faints, cough, a blood spitting. This is rare progressing disease which can result in warm insufficiency and premature death. Today in a pattern about 100 000 people has this disease.
As is the chronic disease, supporting medicinal therapy improves quality of life of patients and decelerates disease progressing. Application for adults the Recommended dose Sildenafilcitrate 20 mg three times per day. Sildenafilcitrate should be accepted approximately with an interval of 6-8 h during time or after food. Application for elderly people For people of advanced age in correction of a dose isn't present need. Application for people with violation of function of kidneys for people with violation of function of kidneys in correction of a dose isn't present need. Application for people with violation of function of a liver for people with violation of function of a liver of an easy and average level in correction of a dose isn't present need. Revacio application wasn't studied at patients with heavy violation of function of a liver.Simultaneous application is donors of an oxide of nitrogen or nitrates in any form. Hypersensitivity is the active substance or to any of fillers.