This medicine contains the active ingredient Finasteride. Finasteride is a synthetic antiandrogen which acts by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to ihydrotestosterone (DHT). It is used as a treatment in benign prostatic hyperplasia (BPH) in low doses, and prostate cancer.
It is a treatment of male pattern hair loss used to treat the symptoms of baldness in men with mild to moderate hair loss on the top of the head and the front of the mid-scalp area. It works only on scalp hair and does not affect hair on other parts of the body.
Finasteride is a synthetic antiandrogen which acts by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). It is used as a treatment in benign prostatic hyperplasia (BPH) in low doses, and prostate cancer.
Finasteride was approved initially in 1992; a treatment for prostate enlargement, but the sponsor had studied 1 mg of finasteride and demonstrated hair growth in male pattern hair loss. In 1997, the U.S. Food and Drug Administration approved finasteride to treat male pattern hair loss.
Finasteride is used in the treatment of prostate cancer, benign prostatic hyperplasia and androgenetic alopecia (male-pattern baldness). Hair loss in a 5-year study of men with mild to moderate hair loss, 48% of those treated with (finasteride) experienced some regrowth of hair, and a further 42% had no further loss. Average hair count in the treatment group remained above baseline, and showed an increasing difference from hair count in the placebo group, for all five years of the study.
finasteride is effective only for as long as it is taken; the hair gained or maintained is lost within 6–12 months of ceasing therapy.
finasteride, even in small concentrations, can cause birth defects in a developing male fetus. The birth defects involve the development of male genitalia (no such effects have been noted in developing female fetuses). On most product inserts, it will be mentioned that the dust or crumbs from broken finasteride tablets should be kept away from pregnant women. finasteride has been shown to be ineffective for treating hair loss in women. However, finasteride tablets supporters respond that the study was on post-menopausal women whose hair loss was more likely related to the loss of estrogen versus a sensitivity to testosterone. Many doctors prescribe it for women, but not without either careful birth control measures or assurance that the woman cannot become pregnant.